We find that lamin A-associated genes are predominantly transcriptionally silent and that loss of lamin association leads to the relocation of peripherally localized genes, but not necessarily to their activation.
In our case the "test-pulse" input was predominantly inactive or "silent" during the local theta-associated activity, and soon after the stimulation it underwent depression.
While intergenic spacers were mostly closed or neutral, actively expressed genes were predominantly open and silent genes were generally closed across the genome.
Conversely, the vast experimental output with predominantly negative or silent changes must undergo exquisitely tight screening to ensure that sperm with deleterious changes are eliminated.
Though the surviving Dickson test involves live-recorded sound, certainly most, and probably all, of the films marketed for the Kinetophone were shot as silents, predominantly march or dance subjects; exhibitors could then choose from a variety of musical cylinders offering a rhythmic match.
Iran is predominantly Shiite.
The typical interphase genome is radially organized with heterochromatin and transcriptionally silent gene regions predominantly restricted to the nuclear periphery (Hochstrasser and Sedat 1987; Rajapakse and Groudine 2011).
Such regulatory regions are often unmethylated within gene promoters of actively transcribed housekeeping genes and tumor suppressor genes, whereas CpG islands of silent genes are predominantly methylated.
Around TSSs, H3.5 was incorporated into both active and silent genes, while H3.3 was predominantly incorporated into active genes (Fig. 8d).
Comparison of the three different lab strains showed that serial passaging of parasites over 10 15 years has resulted in the accumulation of 50 100 SNVs, predominantly in non-coding sequence or as silent mutations with respect to amino acid code.
