PSG induction of alternative monocyte activation is of particular importance as it implies a PSG-mediated switching of the immune system from a predominantly TH1 response to a predominately TH2 response which is more compatible with a successful pregnancy [ 32].
Some studies in murine models show that the eggs are responsible for a predominantly Th2 response.
Therefore, it is highly conceivable that a native Ad5 infection would result in a predominantly antifiber response, as opposed to a dominant antihexon response following intramuscular challenge with Ad5.
This could be because OVA induces a predominantly eosinophilic response that produces a TH2-type immune response with increases in IL-4, IL-5, IL-10, and IL-13 (Erin et al. 2005; Kalomenidis et al. 2005).
The disadvantage of this approach has been that this route of delivery favors the development of a T-helper 2, or predominantly antibody response, whereas a T-helper 1, or cellular immune response is preferred for cancer immunotherapy.
Evaluating the gene expression data together the overall impact of synoviocytes on injured cartilage indicates synoviocytes promote a predominantly anabolic response in chondrocytes potentially to protect from typical degradation in response to injury.
Extensive analysis of the disease has demonstrated that it arises predominantly in response to high-risk etiological challenges, most notably hepatitis virus.
On a probe trial 24 h following task acquisition, rats previously exposed to TMT predominantly displayed response learning relative to control animals.
Relative to control animals, rats exposed to TMT predominantly displayed response learning on the probe trial, and this effect was blocked by neural inactivation of the BLA.
Interestingly, presence of MLG interlayer resulted in predominantly elastic response (as opposed to predominant flow, sans MLG) during lithiation from 2nd cycle onwards.
Overall, pool widening caused a predominantly local response, with change to pool hydraulics and no change in section-averaged velocity in the riffle beyond the initial widening of 10%.
