IDEF1 recognizes the sequence CATGC within IDE1, whereas IDEF2 predominantly recognizes CA[A/C]G[T/C][T/C/A][T/C/A] within IDE2 as its core binding site.
IDEF1 recognizes the CATGC sequence within IDE1, whereas IDEF2 predominantly recognizes CA[A/C]G[T/C][T/C/A][T/C/A] within IDE2 as the core binding site.
Collectively, differences in the patterns and frequencies of polymorphism were noted between bovine TLRs that predominantly recognize viral ligands (TLRs 3, 7, 8, 9) and those that recognize microbial and/or unknown ligands (TLRs 1, 2, 5, 6, 10).
Co-staining with antibodies against the schizont surface protein PIM indicated that anti-SVSP antibodies predominantly recognized SVSPs located inside the schizont rather than on its surface.
While pAb 155 highlighted both nuclear and cytoplasmic NS1 at 8 and 12 h post-infection, mAb 1A7 predominantly recognized only nuclear NS1 at these timepoints.
We show here, for example, that melanoma cells derived from different patients are predominantly recognized by three NKLRs: NKG2D, NKp30 and NKp44 (Figure 5).
This 'within-channel' quantification totally eliminates bias, and clearly confirmed that mAb 1A7 predominantly recognizes nuclear NS1 at the 8 and 12 h timepoints, while pAb 155 recognizes a more even distribution (Fig. 6C).
Recent studies have implicated TLR2 as a critical element in the host protective response to F. tularensis infection, but questions remain about whether TLR2 signaling dominates the response in all circumstances and with all species of Francisella and whether F. tularensis PAMPs are predominantly recognized by TLR2/TLR1 or TLR2/TLR6.
Although dNK cells express various inhibitory receptors of the killer-immunoglobulin-like receptors (KIR) and the C-type lectin heterodimer family (CD94/NKGs), only two NK receptors predominantly recognize the HLA-G molecule; LIR-1 (of the LIR or ILT family) [40], [41] and KIR2DL4 [43], [43].
