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The integration of these data sets with detailed kinetics of IL-4-driven transcriptional changes showed that STAT6 was predominantly needed for the activation of transcription leading to the Th2 cell phenotype.
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In our hands, NB are no more than organic-mineral complexes in fact, they appear as predominantly protein-mineral complexes that comprise the substrates needed for the normal calcium-carbonate-phosphate homeostasis [1] [5].
During transient activation, Erk1/2 remains predominantly cytoplasmic promoting proliferation, whereas its sustained activation is needed for nuclear concentration and results in differentiation.
Power calculations were not needed for the third aim, as this type of evaluation is predominantly descriptive in nature.
For NOD2-dependent signalling, however, CpA blocked NF-κB activation only at concentrations vastly exceeding those needed for depletion of cIAPs, and our data indicate that CpA functions predominantly through antagonizing XIAP's function in the pathway.
Anand Chandrasekher, the chief marketing officer of Qualcomm, a rival technology firm, told Techworld: "Predominantly...you need it for memory addressability beyond 4GB [gigabytes].
Instead, the request for PC was predominantly (56.9%) motivated by psychosocial or nursing-related demands or general support needs for the patient and his/her family.
Moreover around 40% fewer chemicals are needed, predominantly pesticides that are used in growing cotton.
This research offers an urgently needed approach for better managing Malaysian tiger habitat within forest reserves, which are predominantly designated for logging and have weak or non-existent wildlife protection measures.
Thus, dental insurance may contribute significantly to eliminating income disparities in immigrants' unmet dental care needs in the predominantly private fee-for-service Canadian dental care system.
Predominantly, women expressed a need for symptom relief as rationale for their choice.
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