Postsurgical severe AEs were frequent and resulted predominantly in study drug interruptions, reflecting complex tissue and immunological interactions described previously for other multi-target approaches mostly investigated in non-surgical trials (Burges et al, 2007; Kaye, 2007).
Our meta-analysis has shown that significant association between vitamin-D metabolites and breast cancer were predominantly seen in studies where blood levels were collected after breast cancer diagnosis.
This Sense of Control measure has been predominantly used in studies on health and well-being, including in the longitudinal study of Midlife in the United States (MIDUS II), and to our knowledge (Lachman and Weaver, 1998; Inter-University Consortium for Political and Social Research [IUCPSR], 2006), we are the first to use it as an indicator of decisional balance for leadership.
Unlike the spectroscopic techniques used predominantly in dissolution studies, electrochemistry allows for the determination of mass transfer data beside solubility values.
It allows for time-lapse examination of lysosomal Ca2+ store depletion and refilling with acute (<5 min) application of various pharmacological reagents, which has many advantages, including amenability to prolonged treatment protocols, as have been used predominantly in previous studies.
Several coping strategies were described in the literature, predominantly in qualitative studies.
Systematic analysis of the association between miRNA-related SNPs and cancer risk has been reported predominantly in two studies.
In contrast, these kinds of anomalies have often and predominantly been observed in studies investigating maternal alcohol consumption or solvent abuse during pregnancy [ 11, 12].
The mutually exclusive distribution of H3K27me3 and H3K9me3 described above has predominantly been shown in studies of constitutive heterochromatin loci, and in all cases, this clear separation of domains has been seen for trimethylation marks.
In the pediatric group the survival rate in the predominantly American studies, in which treatment was mainly performed by EMS at the trauma scene (n = 1,123 patients from 9 studies, mortality 79.7%), was significantly lower compared to the European investigations where treatment was mainly administered by physicians at the scene (n = 120 patients from 4 studies, mortality 92.5%) (P = 0.0012).
