Sentence examples for predominantly immune from inspiring English sources

In mammals, the classical MHC consists of a large number of linked genes (e.g. greater than 200 in humans) with predominantly immune function.

Although those early array platforms contained few immunologically relevant genes, the transcripts that differentiated responding from non-responding metastases had predominantly immune function.

The opposite was true for genes with highly variable expression, whose GO terms were predominantly immune functions such as innate immune system and interferon stimulation.

Furthermore through recruitment and activation of stroma cell populations, pancreatic cancers generate a predominantly immune -suppressive microenvironment [ 8] T-cell responses are partially regulated by dendritic cells, which take up antigens.

Although initially there is skepticism regarding the origin of imbalance of activated and apoptotic endothelial-derived MP in patients with impaired glucose metabolism and dyslipidemia, we suppose that inflammatory cytokine overproduction and probably lipid abnormalities may consider a possible cause of predominantly immune phenotype of MPs not directly related with glucose impairment.

Previous histologic analysis of skin from SSc patients showed small pericapillary lymphocytic infiltrates [ 3]; however, it is not clear whether a specific immune response signature of the skin microenvironment occurs in SSc or whether the skin inflammation is governed by a predominantly immune response.

It has been described that the activation of certain Toll-like receptors can polarize MSCs to switch from a predominantly immune-suppressive MSC2 (Toll-like receptor3-primed) to a proinflammatory MSC1 (TRL4-primed) phenotype (40, 41).

A panel of 15, predominantly immune-related genes were chosen for validation of the NGS data by qRT-PCR in both HC and CE samples at 7 and 21 DPP.

In this study, the authors found that there is a difference in LPS-stimulated gene expression in MDD patients versus controls, leading to the identification of a predominantly immune-related biomarker with 87.5% sensitivity and 61.5% specificity to differentiate between cases and controls.

These SNPs are in a variety of genes, but are associated predominantly with immune system and immunity-related genes.

Numerous predominantly innate immune cells perform phagocytosis (e.g., neutrophils, monocytes/macrophages, dendritic cells) [48].