The predominantly high fertility rates in developing countries, 4 especially in sub-Saharan Africa, are connected to low contraceptive use. 2 5 The effect of high fertility on women and families is enormous.
CONCLUSIONS: In a large outbreak of E. coli O157 H7 infections among visitors to a dairy farm, predominantly children, high rates of carriage of E. coli O157 H7 among calves and young cattle most likely resulted in contamination of both the animals' hides and the environment.
In diploid cells in which the second copy of the genome sequence is present, loss of heterozygosity (LOH) occurs at a high rate, predominantly through allelic crossover but also via gene conversion and chromosome loss (Ohnishi et al. 2004).
Later Warburg et al. of the Kaiser Wilheim Institute fur biologie described what was later known as the Warburg effect where energy is predominantly generated by a high rate of glycolysis followed by lactic acid fermentation in the cytosol, even in the presence of plentiful oxygen.
The conversion time curves exhibit, independent of the stabilizer, an initially high rate where predominantly MMA is polymerized and a second period with slower rate dominated by LMA consumption as proven by 1H NMR spectroscopy and DSC data.
We attended a selected patient population of predominantly in-patients, with a high rate of TB and HIV co-infection and advanced disease which may be due to late presentation to and late referral from a health centre, factors well known to worsen TB treatment outcome [35] [38].
Scientific literature indicates that cancer cells predominantly generate energy by a high rate of glycolysis rather than the Krebs cycle of mitochondrial metabolism even when oxygen is abundant, which is called Warburg's effect [ 1].
Moreover, it is a well-known fact that most cancer cells predominantly produce energy by a high rate of glycolysis followed by lactic acid fermentation in the cytosol [ 30, 31].
Another mechanism could be chronic hyperglycaemia that could increase the breast cancer risk, for instance, via the Warburg effect (Warburg, 1930; Brown and Simpson, 2010), that is, the mechanism by which cancer cells predominantly produce energy by a high rate of glycolysis in the cytosol rather than by glycolysis followed by the oxygen-dependent Krebbs cycle in mitochondria.
Limpopo province has a population of 5.5 million, and is predominantly rural, with high rates of poverty and poor access to basic services[ 17].
