Sentence examples for predominantly functioning from inspiring English sources

Disruption of the Cd36 gene affected the early and peak mycobacterial burdens, but did not appear to impact the ultimate clearance of the organism, consistent with the role of CD36 as a receptor predominantly functioning in innate immunity[ 62].

Results from a genome-wide analysis of the host intracellular network that regulates survival of Mtb showed that those factors predominantly function through the regulation of autophagy (Kumar et al., 2010).

To improve understanding, we drew on a global catalytic model and previous findings to design three NOS chimeras that may predominantly function as NO dioxygenases: iNOSoxy/nNOSred (Wild type (WT) chimera), V346I iNOSoxy/nNOSred (V346I chimera) and iNOSoxy/S1412D nNOSred (S1412D chimera).

Our own data suggest that CovR of S. mutans predominantly functions as a repressor [27], [29], [30].

Both receptors predominantly function as non-covalently bound homodimers.

CtBP family proteins predominantly function as transcriptional factors.

Members of the 14-3-3 14-3-3 14-3-3oteukaryotic proteinnantly familyon as dimers.

Conversely, Gli2 predominantly functions as an activator in Hh pathway, Gli2 knockdown is able to inactivate Hh signaling and mimic the phenotypes of Shh mutant.

The MCM proteins predominantly function in DNA replication, and mutants therefore have consequences resulting in defective proliferation, genome instability and cancer.

These data imply that p14ARF predominantly functions by impeding ribosome biogenesis, causing an increase in the levels of nonribosomal 5S RNP.

Moreover, the finding that expression is comparably higher in intestinal/excretory tissues than in the carcass suggests that this transporter predominantly functions in midgut, or in Malpighian tubules.