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The MCM proteins predominantly function in DNA replication, and mutants therefore have consequences resulting in defective proliferation, genome instability and cancer.
In addition, the types of word these events occur on are predominantly function in type (Au-Yeung, Howell & Pilgrim, 1998; Au-Yeung, Vallejo Gomez & Howell, 2003; Bloodstein & Gantwerk, 1967; Bloodstein & Grossman, 1981; Dworzynski, Howell, Au-Yeung & Rommel, 2004; Howell, 2004b; Howell, Au-Yeung & Sackin, 1999).
Similar(58)
Moreover, the finding that expression is comparably higher in intestinal/excretory tissues than in the carcass suggests that this transporter predominantly functions in midgut, or in Malpighian tubules.
Disruption of the Cd36 gene affected the early and peak mycobacterial burdens, but did not appear to impact the ultimate clearance of the organism, consistent with the role of CD36 as a receptor predominantly functioning in innate immunity[ 62].
Two families of DNMTs have been identified: DNMT1, which predominantly functions in maintenance of DNA methylation during DNA replication, and DNMT3 (including DNMT3a and DNMT3b), which is thought to be primarily responsible for de novo CpG methylation [10].
All four pairs showed significantly reciprocal expression patterns, consistent with the observation that miRNAs in mammalian predominantly function to decrease target gene levels [ 48].
The elevated SHP-1 concentration in MZ B cells causes FCRL5 to adopt predominantly inhibitory function in this subset.
Since regulated necrosis triggers necroinflammation [ 65], it is conceivable that also these processes of ROS-driven parenchymal damage may contribute to overall organ damage, obviously with a predominantly important function in the kidney [ 3, 63].
Here we found that, overall, NJ provided more biologically sound results than UPGMA: the first two groups in the NJ-tree comprised brain tissues and endocrine glands; muscle and fat tissues have a predominantly structural function in the body, while the rest of tissues (liver, stomach, ileum and blood) have an important metabolic role.
Conversely, Gli2 predominantly functions as an activator in Hh pathway, Gli2 knockdown is able to inactivate Hh signaling and mimic the phenotypes of Shh mutant.
This is the establishment of critical green corridors that should be preserved and maintained for predominantly ecological functions, in advance of or in conjunction with new development.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com