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Karimi, M. M. et al. DNA methylation and SETDB1/H3K9me3 regulate predominantly distinct sets of genes, retroelements, and chimeric transcripts in mESCs.
Caenorhabditis elegans, Drosophila melanogaster and Mus musculus mutants lacking ADAR enzymes display predominantly distinct neurological phenotypes [ 5- 8].
While glycoprotein G molecules from HSV-1 and HSV-2 are predominantly distinct immunologically, there are regions of sequence homology and this effect cannot be definitively ruled out [ 11, 12].
In contrast, ATP hydrolysis is required to observe an HES population at the degenerate NBS as inferred from the predominantly distinct distributions in the presence of AMP-PNP and ADP-Vi.
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Confirming earlier experimental and computational work, a structural analysis reveals that poly-alanine regions in silk predominantly form distinct and orderly β-sheet crystal domains while disorderly regions are formed by glycine-rich repeats that consist of 310-helix type structures and β-turns.
Overall the data indicate that fatty acid concentrations above and near the CMC lead to show maximum differences in the aggregation rates and generate predominantly two distinct oligomeric species of Aβ42: 12 18 mers and 4 5 mers.
The grade II PXAs histologically fell into two general types: those that had predominantly a distinct mesenchymal-like growth pattern with fascicular and sometimes storiform growth pattern (PXA (m)) (Fig. 1A and B) and those that predominantly had a diffuse fibrillary background (Fig. 1C and D).
Together these results demonstrate that even though stefin and cystatin genes map predominantly to distinct chromosomal clusters and encode two divergent sets of proteins, they present an assortment of expression profiles sharing both intra- and inter-group similarity in mouse tissues.
We conclude that ChdA, ChdB and ChdC predominantly regulate distinct gene sets during growth.
The proteins grouped as TamB predominantly showed distinct sequence relationships according to their taxonomic species of origin (fig. 2 and supplementary fig. S2, Supplementary Material online).
Strikingly, poly-GA, the most abundant DPR species in patients [ 35, 36], predominantly formed distinct dot-like or star-shaped inclusions in the cytosol (Fig. 1) and occasionally in the nucleus (Fig. S2a).
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