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Historically, analysis of mutation patterns to investigate underlying DNA damage and repair processes in human cancers has predominantly been restricted to reporter cancer genes, notably TP53.
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Between 70%and90%0% of ASCC are associated with HPV type 16 in single or mixed infections; the contributions of other HPV genotypes are not well established, but may predominantly be restricted to a small subset of causative genotypes.
Conserved regions are restricted predominantly to the ∼300 aa catalytic DMT domain.
We demonstrate Plp promoter driven Cre expression is restricted predominantly to mature oligodendrocytes of the central nervous system (CNS) at postnatal day 28.
PPARγ2 is restricted predominantly to adipose tissue where it is crucial for adipogenesis, but the adipogenesis seen in PPARγ splice variant-null fibroblast cell lines suggests functional similarity between the isoforms [42].
Microscopic examination of both wholemounts and tissue sections revealed that β-gal activity, and hence Pea3 expression, was restricted predominantly to the myoepithelial cells comprising the outer epithelial layer of the mammary ducts (Figures 2B and C), as previously reported [70].
Analysis of T-box distribution confirmed that the element is restricted predominantly to species of the phylum Firmicutes.
We also found evidence that other molecular mechanisms involved in modulating glucose homeostasis are restricted predominantly to subjects from one ethnic origin.
Alternatively, in the chronic stage, when parasites are restricted predominantly to gastrointestinal sites (24), they may be less accessible compared to the acute stage, when parasites can be targeted in all organs, although this explanation is less likely given the pharmacokinetic and distribution properties of posaconazole (30).
In this study we show that ARR22 is a predominantly cytoplasmic protein, whose expression is restricted to the chalaza of developing seeds.
In kidney biopsies from control renal tissue, HMGB1 expression was predominantly negative or, if present, was restricted to the cell nuclei.
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