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Specifically, positively charged and neutral NPs are absorbed by all cell types at the same rate, whereas negatively charged ones predominantly accumulate in tumor cells [93].
In individuals with experimentally induced or naturally acquired TSEs prion infectivity and PrPTSE predominantly accumulate in the CNS but were also found, to varying degrees, in peripheral tissues [2], [10] [12].
Similarly, although waxes can be detected in beans and flowers, these compounds predominantly accumulate in leaves.
Previous analyses have shown that PSII components predominantly accumulate in the M cells of the maize leaf [ 8, 9].
In contrast, the pot-miRNAs targeting the GA3oxidase1 gene predominantly accumulate in the endosperm where the target is also actively transcribed.
Surprisingly however, H3K14ac and H3K4me3 were found to predominantly accumulate not at the 5'-end but at the 3'-end of the nanochromosomes while the distribution of H3K4me1 remained unchanged.
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Experiments on mice have shown that cadmium predominantly accumulates in the liver, kidneys, and spleen, whereas tellurium accumulates almost exclusively in the kidneys [126].
The stability of 125I-ND was greater than 90%% within 25 h, and the in vivo distribution showed that ND predominantly accumulated in the liver, spleen, and lung.
Whole-animal in vivo tracking studies revealed that irrespective of surface modifications, graphene predominantly accumulated in lungs over a period of 24 h.
This lipophilic cationic imaging probe predominantly accumulates in the mitochondria, where it is retained in response to the electrical potential generated across the membrane bilayer [15]-[17] [15]-[17]
Zhang et al. [95] showed that CdTe QDs predominantly accumulated in the liver, decreasing the amount of antioxidants in it and inducing oxidative stress in liver cells.
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