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Since the predominant variant of onset detection is a novel issue, a comparison to existing approaches is difficult.
PV was the predominant variant of pemphigus in the present study (95.4%).
The predominant variant of transcripts encodes p120 (BRD8 isoform 1), a coactivating factor for thyroid hormone receptor (Monden et al, 1997).
Here, we found that the predominant variant of TNC in RA serum was 320 kDa in mass, suggesting that this constitutes the large isoform possessing all nine alternatively spliced TNIII repeats.
Using an ELISA assay, we observed that the average 5mC level was significantly higher (5.5% methylation) than that of 5hmC (0.63% methylation) in the brain DNA sample, supporting previous reports of 5mC as the predominant variant of methylation (Fig. 6a ).
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This result is in agreement with our previous analysis [4] in which the predominant variants of type 1 iodothyronine deiodinase (DIO1) found in ccRCC were those resulting from distal 5' splice site usage.
Two predominant variants of the hemochromatosis (HFE) gene account for most cases: the C282Y and H63D variants, which are common in the U.S. population, with a prevalence of 7 17% and 10 32%, respectively (Bradley et al. 1998).
A similar finding has been described for major house dust mite allergens, where the predominant variants of Der p 2 have been found to be distinct in different regions [ 26].
However, the presence of only E2-211T in three of three sequences with the E1-226A [2] circumstantially indicates that E2-211T was probably the predominant variant on Reunion Island.
In general, the distribution of /dz/ realization in the Mix dialect seems to parallel nicely with that in the Chiang dialect, with [z]/[dz] being the predominant variant for old speakers and [l] becoming the predominant variant for young speakers.
However, six of the remaining eight H30-Rx isolates, from two participants, formed a distinct PFGE cluster, Cluster B. It is of interest that this variant was not entirely displaced by the predominant variant; thus, two variants of the H30-Rx subclone were circulating in the LTCF.
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