This behavior of the NHPs in the setting of repeated social separation stress parallels clinical depression, as interpersonal loss is the predominant trigger of depression in humans [35] and chronic stress is a major epidemiological risk factor for major depression and chronic anxiety disorders [37].
However, there is increasing evidence that the systemic inflammatory response per se is a predominant trigger of AF in critically ill patients.
Subsequently, damaged necrotic tubular cells act as the predominant trigger for amplification of the inflammatory response by damage-associated molecular patterns (DAMPs), which initiate the influx of various inflammatory cells into the kidney (Kulkarni et al., 2014).
TLR2 rather than TLR4 is the predominant receptor triggered by TB [15], however, both receptors follow a similar signal transduction pathway requiring TIRAP.
An increase in intracellular free Ca2+ (concentrationtratisn is the predominant mechanism triggering the fluid secretion from acinar cells (Melvin, 1999), whereas PKC activates the secretion of low amounts of proteins in the saliva (Tojyo et al, 1992).
Results indicate that although point mutations generate most of the new protein haplotypes, recombination is a predominant force triggering diversity since the very first steps of protein evolution, causing at least 50% of the total amino acid variation observed in recently diverged proteins.
FcγRIII is the predominant receptor in triggering immune effector functions following murine IgG1-IC binding [22].
While remote seismicity triggering at volcanoes seems predominant, other regions of triggering include Wakayama, Tottori and Noto Peninsula, which correspond to active fault areas (and no volcanic activity).
In our previous study, we found that PVA was extremely common in mechanically ventilated children and the predominant type was ineffective triggering [4].
Apoptosis is the predominant form of cell death triggered in vivo and in vitro by drugs in hematologic malignancies [13].
