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Developing states engaged in a defensive regionalist project to improve their collective negotiating power with predominant states in the global political economy can be faced with a divide-and-conquer strategy in interregional and multinational negotiations.
Here, the binding affinities of seven aliphatic cyclic ureas to HIV-1 protease are calculated using a predominant states method and an implicit solvent model based upon finite difference solutions of the Poisson-Boltzmann equation.
Subsequently in a multiple linear regression model we estimated the adjusted influence of CBL for each NBAS cluster score by including the covariates mentioned above, the initial and predominant states of arousal (Table 2).
For this purpose, we first conducted analysis of covariance (ANCOVA) using each NBAS cluster as the outcome and CBL as the predictor – first alone (unadjusted analysis) and then using initial and predominant states as covariates (adjusted analysis).
We also considered whether the association of CBL with each NBAS cluster is specifically influenced by the potential effect of the initial and predominant states of the newborn on the NBAS cluster scores and found, using ANCOVA, that it was not (see additional file 1, supplementary table 2).
It was essential to include both initial and predominant states in the multiple regression models because there two variables were not completely collinear with each other indicating that in a given infant often the initial state was not the same as the predominant state (Spearman's rho = 0.093, p = 0.1938).
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There is now no need, he says, as there was in the Duke of Zhou's day, for one predominant state.
While the active conformation of the kinase is not forbidden and can be visited transiently, it is not the predominant state.
Results indicate that the fraction of the CrN phase increases with increasing bombarding energy from 4 to 8 to 12 keV, and reaches a predominant state.
The LF/HF ratio shows an increase under stress, which indicates a predominant state of the sympathetic nervous system under stress-inducing conditions (e.g., Hjortskov et al. 2004; Isowa et al. 2006).
Obviously, in higher S and lower d (Figure 11(a)), mode-III was dominant almost between load and support points (G III /G = 79%) while, in lower S and higher d (Figure 11(c)), mode-II was the predominant state of crack growth (G II /G = 68%).
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