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But a major achievement has been the development of total mesorectal excision (TME) as a surgical standard and the recognition that the surgeon is the predominant prognostic factor.
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To date, clinical stages, pathologic findings, and performance statuses have been considered the predominant prognostic factors in patients with common solid tumors.
As well, in our model, coefficients were higher for clinicopathological characteristics than for biomarkers, so regional lymph-node involvement and distant metastasis were still predominant prognostic factors in ESCC.
The predominant established prognostic factor of cancer survival is stage at diagnosis, as the classification of stage is derived from expected survival probability.
Previous reports have strongly supported the role of the predominant histologic subtype of the "primary lung tumor" as a prognostic factor.
Respiratory germs are less predominant than S. aureus and enterobacteriaceae and lung infection is not a prognostic factor (since only age and performance status were predictive of antibiotic treatment failure).
DSOF may be a useful prognostic factor for severe sepsis.
Tumor spatial heterogeneity is an important prognostic factor.
Furthermore, solitary liver metastasis is a significant prognostic factor [12 14].
Similarly, comorbidity was not a prognostic factor in our study.
Low PbtO2 is in itself an independent prognostic factor.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com