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When interpreted in the context of prior information, our results suggest that the overall patterns of differential protein expression obtained from limited samples can still aid in clinical decision making by providing an estimate of the predominant pathways that underpin cellular phenotype.
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Glycolysis is a basic metabolic process with crucial importance in plants because it is the predominant pathway that 'fuels' plant respiration.
They also show that signalling via the Tumour necrosis factor (TNF; also known in Drosophila as Egr) ligand is the predominant pathway that activates JNK on Rok activation.
Furthermore, we show that signalling via the Tumour necrosis factor (TNF; also known as Egr -ligand JNK pathway is most likEgr -ligand JNKnant pathway that actisates JNK upon Rok activation.
Gefitinib, a more targeted form of treatment that inhibit the predominant pathway(s) that initiate and maintain the carcinogenic process may make this biological difference between tobacco-induced and nontobacco induced lung cancer more manifest.
The reaction of CO2 with this highly basic tertiary amine occurs by two pathways: (1) a minor path via the CO2 reaction with hydroxide ion and (2) a predominant reaction pathway that can be characterized by its first order dependency on the free amine concentration.
For each type of sulfated product, there is a predominant fragmentation pathway that results in a characteristic product ion during MS/MS fragmentation.
GO and pathway analyses were performed to determine the predominant biological processes and pathways that are potentially regulated by the candidate genes and play a role in hypoxia tolerance.
To gain an overview of the predominant molecular functions and biologic pathways that were regulated at the transcriptional level during the uterotrophic response to E2, we interrogated the 3,538 E2-responsive genes using the GOStat gene ontology mining tool (http://gostat.wehi.edu.au) (Beissbarth and Speed 2004).
A strong consensus is not yet available regarding the predominant pathway(s) that underly miRNA gene repression [ 41- 44].
There were also a number of pathways that had a predominant positive or negative correlation with DMFS.
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CEO of Professional Science Editing for Scientists @ prosciediting.com