Sentence examples for predominant gene expression from inspiring English sources

Principal components analysis (PCA) was used to reveal trends in the data and to identify predominant gene expression patterns.

EGFR status was determined by fluorescent in situ hybridization and immunohistochemistry. Using unsupervised clustering algorithms, the predominant gene expression signatures correlated with the histopathological grade but not with EGFR protein expression as detected by immunohistochemistry.

To further test the hypothesis that gene methylation differences among tissues were correlated with tissue predominant gene expression, we interrogated our methylation data using lists of genes determined to have high tissue-predominant ("biased") expression based on calculations in Rodgers-Melnick et al. [ 49].

The numbers of differentially expressed genes after UV were considerably higher than after IR or MS. Remarkably, after all three stressors the predominant gene expression response in CM-enriched fractions was up-regulation, while in fibroblasts genes were more frequently down-regulated.

From the ages of 21 to 78 weeks, sex-predominant gene expression was higher in males than females.

In contrast, SL scaffolds displaying a bigger pore size, higher porosity and crystallinity resulted in homogenous cell distribution, increasing cell proliferation and advanced chondrocyte differentiation in terms of their spherical morphology, predominant chondrogenic gene expression and abundant cartilaginous extracellular matrix production.

Furthermore, the association of LOXL2 expression with basal-like breast tumours was confirmed in studies using breast cell lines showing that LOXL2 expression was only observed in those previously sub-classified as basal B/mesenchymal subtype with predominant mesenchymal gene expression and enhanced invasiveness (Blick et al, 2008; Charafe-Jauffret et al, 2006; Neve et al, 2006).

The predominant changes in gene expression identified by cluster analysis were metabolic biological processes as well as changes in the mitochondria and myosin complex.

For some of the clusters, this analysis allowed predictions of the predominant location of gene expression.

The predominant variation in gene expression was according to developmental stages rather than morphotype differences.

Here, differences between the two cell populations are observed in the predominant type of gene expression response, i.e. up-regulation versus down-regulation.