Sentence examples for predominant downstream effector from inspiring English sources

Our bioinformatics analyses indicated that ATF2 is the predominant downstream effector of PLK3.

Although the VEGF receptors share considerable overlap in ligand binding, downstream effector interaction and biologic function, predominant actions have been identified.

E-Cadherin/catenin signaling has long been known a downstream effector of EGFR signaling [15 18].

The downstream effector of PHD1KDM5B is therefore required for the KDM5B-induced demethylation of H3K4me2/3.

Inhibition of the downstream effector Gli has also received much attention.

The same effect was obtained by blocking the common downstream effector Akt.

dHand cannot be directly regulated by Isl-1, but can be regulated by BOP, a downstream effector of MEF2c.

TCTP cannot affect downstream effector cells until it is secreted.

ROCK is a major downstream effector of RhoA GTPase.

PI3 kinase is a known downstream effector of PDGFRβ2.

Tyrosine phosphorylated IRS1 then recruits downstream effector molecules which in turn activate further downstream signalling pathways.