Sentence examples similar to predominant dose limiting from inspiring English sources

The predominant dose-limiting toxicities (DLTs) were reversible neutropenia, febrile neutropenia and thrombocytopenia (Mross et al, 2008; Hofheinz et al, 2010; Frost et al, 2012).

Neurotoxicity was also found to be the predominant dose-limiting toxicity in another oxaliplatin-containing regimen for gastric cancer (Louvet et al, 2002).

The predominant dose-limiting toxicity encountered in two of three patients treated at 20 μg/kg was transient liver toxicity, as indicated by a grade 3 4 elevation of serum liver enzymes (patient N10, ALT grade 4, AST grade 3; patient N12, ALT grade 3).

IRs were dose limiting above 250mg.

Dose limiting toxicity was not experienced.

One dose limiting toxicity occurred at dose level 2 (prolonged thrombocytopenia), and the recommended phase 2 dose was established at 30mg twice daily.

Doses for capecitabine, oxaliplatin and everolimus were modified per dose limiting toxicity (DLT).

Hematological toxicity was dose limiting and correlated with the administered 131I dose.

Thrombocytopenia was dose limiting, but highly variable among patients at a given dose level; other toxicity was mild and uncommon.

Hematopoietic toxicity is dose limiting for most radiolabeled immunoconjugate therapy.

Thrombocytopaenia was dose limiting.