Sentence examples for predominant consequence of from inspiring English sources

The predominant consequence of this accumulation is the activation of proto-oncogenes or silencing of tumor-suppressor genes [ 58].

Unexpectedly, the predominant consequence of c-Myc activation was shown to be the widespread repression of miRNA expression, probably as a direct result of c-Myc binding to miRNA promoters [ 73, 89].

Thus, we rather interpret the PE reduction in psd1Δ and psd2Δ as a predominant consequence of their primary loss of enzymatic function and not as a result of the dead cell population.

A predominant clinical consequence of HIV that persists despite treatment is its neurological effects, which are collectively referred to as HIV-associated neurocognitive disorders (HAND) and occur in approximately 50% of infected individuals.

In the first year, initial discriminatory ability reflecting a universal sensitivity to the sounds of all human languages narrows as a consequence of predominant exposure to one's native language and scarce exposure to other languages (Werker & Tees, 1999).

In contrast, GAD65 dysfunction may be the consequence of a predominant vulnerability of neuronal pathways in the amygdala-hippocampal complex, according to the findings in the animal models with genetic modification of GAD65 expression (15 26; see above).

Similar to U2OS and Cl2 6 cells there was no major change in p53 protein level in cells treated with RPS9 siRNA (Figure 7E), but we found that p21 protein was reduced in RPS9 knockdown HeLa cells, presumably as a consequence of the predominant apoptotic response.

In SLE patients treated with MMF it is probably the consequence of a predominant and fast inhibiting influence of mycophenolic acid on the synthesis of plasmablasts [ 16, 17].

As a consequence of the predominant use of anti-RAS versus other drugs, only a mild decline of BP values from the referral visit was observed.

However, probably as a consequence of its predominant function in stimulating cell proliferation, deregulation of the TrkA pathway is common in cancers [ 5].

However, in most physiological settings the enzyme exhibits predominant reductase activity as a consequence of the coincident expression of hexose-6-phosphate dehydrogenase (H6PDH), which facilitates enhanced, localized concentration of the cofactor for 11β-HSD1, NADPHy nicotinamideinadeninedinucleotideleotide phosphate, reduced form), within the endoplasmic reticulum lumen [ 7].