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The presented tree topologies show predominant clustering of monomers derived from the same array.
Predominant clustering of the tumor entities to their corresponding tumor class is indication for the robustness of the tumor phylogeny.
Molecular analysis revealed one predominant cluster of A. baumannii isolates among other minor ones, probably reflecting endemicity and cross-transmission [ 50].
In this analysis, almost all individuals demonstrated membership of multiple clusters, but some populations displayed membership of predominant clusters that corresponded to geographical affiliation.
Interestingly, five heterosexual predominant clusters were comprised mainly of females, including one large cluster (n = 7) where 86% individuals were female.
PFGE comparison of isolates from a predominant cluster in South Africa with an isolate from the Hajj outbreak showed that they were related (data not shown).
Then, it performs an N-D clustering on the metadata to search for predominant clusters.
In all cases, we observed 2 predominant clusters, and there was no statistically significant difference in overall survival between these 2 predominant clusters in any of the datasets.
All predominant clusters apart from CAS1 strains were equally distributed in the country suggest a continual transmission of strains.
At K = 2, an East-West cline of cluster assignment was observed in North America, and the predominant cluster in western North America (in green; Fig. 3B) was also found in Eastern Europe, Beijing and the two Australian populations.
The results further show an ageing of the samples that causes predominant cluster adsorption most likely of water at oxygen surface groups.
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