The two complete and annotated genomic DNA sequences of V. vulnificus belong to strains of clade 2, which is the predominant clade among clinical strains.
The vast majority of studies that have contributed to our current understanding of CD4+ T cell immunology in HIV-1 infection have been conducted in the context of clade B infection, which is the predominant clade in North America and Europe.
Data indicate that FIV, from within the U.S., localize to four viral clades, A, B, C, and F. Also shown is the geographic isolation of strains where clade A and clade B are found predominately on the west coast; however, clade B is also found throughout the U.S. and represents the predominant clade.
However, most information has been derived from studies of subtype-B-HIV-infected Caucasian and subtype-C-HIV-infected African populations, and very little information is available on the CRF01_AE virus, the predominant clade circulating in southeast Asia [16], [17].
Viruses in clade 2 or its subclades have become the predominant clade in human infections since 2005.
In Vietnam, subclade 2.3.4 first appeared in humans in 2005 and has been the predominant clade since 2007.
However, the predominant clades in the rest of the world, where the majority of HIV-1 infections occur, are non-B variants.
Of 28 samples sequenced in both genes, the predominant clades were CRF02_AG (39%) and HIV-1G (32%).
Clustering of BH3 response profiles from NB mitochondria identified three predominant clades, or BH3 response classes.
Predominant clades obtained were further analyzed to distinguish between "ancestral" versus "modern" lineages of tubercle bacilli based on the presence or absence of the TbD1 region.
