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The increased production of reactive oxygen species, particularly H2O2, by cancer cells is likely the result of mitochondrial dysfunction, as mitochondria are considered to be the predominant cellular source of reactive oxygen species [8].
Collectively, these results demonstrate that EA treatment reduces the adipose macrophage infiltration, thereby reducing the percentage of macrophage number, a predominant cellular source of inflammatory adipokines, which may in turn explain the reduced mRNA levels of TNF-α, MCP-1 and IL-6 in the obese group.
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CD4+ Th2 cells are the predominant cellular sources of IL-5 [5].
The aim of the present study was therefore to identify the predominant cellular sources of cytokines in RA by comparing their expression across five populations in RA synovial fluid and peripheral blood.
i) Cellular source of TNFα production Cellular source of TNFα production Intracellular cytokine staining monocytes from TB patients revealed the predominant producer of TNFα in whole blood to be the 'classical' monocyte phenotype, staining strongly for CD14 and weakly for CD16 (CD14hiCD16lo monocytes).
Since in situ hybridization studies have demonstrated that alveolar type II cells are the predominant source of VEGF within the lung, this correlation supports type II epithelial cells as the main (but not necessarily sole) cellular source of KL-6 within the lung in ARDS.
Nodulation, which begins with the formation of cellular microaggregates, is the predominant cellular defense reaction to bacterial infections in insects.
The cellular source of IL-12 could also differ.
Mitochondria are main cellular source for energy in eukaryotic cells.
The female gene sub-network identified angiogenesis, growth and apoptosis as predominant cellular processes affected.
In all positive cases the predominant cellular localization for expression was cytoplasmic.
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