Sentence examples for predominant activator of from inspiring English sources

In gastrointestinal malignancies, transcriptional up-regulation of HH ligands has been identified as the predominant activator of HH signaling in these diseases (reviewed in [3]).

These results suggest that GefE is the predominant activator of RasD and is specific for RasD.

Vascular endothelial growth factor (VEGF) is a predominant activator of endothelial cell functions such as new blood vessel formation (angiogenesis) during development [ 6].

The predominant activator of PAR-1, thrombin, binds to the receptor N-terminus LDPR41−S sequence and cleaves the R41−S peptide bond [ 12].

The predominant activators of PARs in cancer cells are thrombin, MMPs, trypsin, TF, FVIIa, FXa, and their ternary complex TF/FVIIa/FXa [ 5, 15, 16].

CNX-012-570 is a highly potent and direct activator of AMPK with half maximal effective concentration (EC50) of 93 nM towards α1β1γ1 isoform (predominant isoform in liver and adipose tissue) and 285 nM towards α2β2γ3 isoform (predominant isoform in skeletal muscle) (Additional file 1A & B) as established using recombinant AMPK heterotrimer complexes.

Lubiprostone, a selective activator of type 2 chloride channels, is approved for treatment of chronic idiopathic constipation and recently constipation-predominant irritable bowel syndrome.

She was prominent in the Los Angeles community as a long-time advocate and activator of the arts, education and health.

Receptor activator of nuclear factor κB ligand.

Mn2+ was the activator of neutral proteinase.

Mn2+ was an activator of neutral proteinase.