Despite the recognition by clinicians for over a century that a hereditary predisposition to cancer exists in certain families, the possibility of utilising this information to help these patients has only become available in the 1990s with the discovery of cancer susceptibility genes (Steel et al, 1999).
Is it a predisposition to be feckless and lazy?
It is supposed that a genetic predisposition is more likely to exist, followed by the environmental assaults imposed by the respiratory illness itself and the direct neuropsychiatric effects of chronic respiratory disease [ 7].
Given the wide role of sPLA2 in many critical respiratory conditions, an individual predisposition due to different polymorphisms is likely to exist.
However, only about 13% of such individuals develop WE, raising the possibility that a genetic predisposition to WE may exist in some individuals [ 31].
The girls were only four and seven when Alice was operated on, but when they got old enough to understand she sat them down and told them that, given her illness, we had to face up to the possibility that a genetic predisposition to lung cancer existed in our family.
There is compelling evidence that a genetic predisposition to preterm birth exists [ 71, 72].
Hence, a dual regulatory capacity, dependent upon the genetic predisposition to trait anxiety, exists in prefrontal-amygdala areas.
For over a century clinicians have been aware that a hereditary predisposition to develop cancer exists in certain families (Steel et al, 1999).
However, the increased rate in some ethnic groups and some families, and the observation that siblings of patients with meningitis can have deficient antibody synthesis against H. influenzae, indicate that genetic predisposition to infection probably exists [ 43].
We hypothesized that breed predisposition to canine gastric carcinoma exists in dogs.
