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Whether these patterns of methylation contribute to tumorigenesis in aged tissues – namely, as markers for predisposition to acquiring genetic and/or epigenetic changes associated with tumor development – remains to be determined.
It has also been demonstrated that rare somatic events, such as a chromosome 20q deletion or loss of heterozygosity on 9p, have occurred more than once in subclones from the same patients, suggesting that the myeloproliferative disorder clone carries a predisposition to acquiring such genetic alteration [ 13].
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As the chart shows knowledge (or rather, presumably, an innate predisposition to acquire such knowledge) is highly genetically determined.
In Colombia, no studies have been conducted to identify autochthonous genetic factors related to the predisposition to acquire single or multiple HPV infections to date.
The resulting massive gene dosage modifications could explain their predisposition to acquire paclitaxel resistance.
This may help to determine whether MSC preparation varies in terms of predisposition to acquire a pro-inflammatory phenotype or whether this is an acquired characteristic as a result of contact with the patients' cellular environment.
As indicated earlier, some fearful, timid, socially withdrawn children inherit a temperamental predisposition to develop this form of behaviour; other children, however, acquire it as a result of a stressful upbringing, experiences, or social circumstances.
Thus, all other things being equal, a predisposition to adopt the more common variant increases the chance of acquiring the most adaptive variant.
They have an innate predisposition to learn song; they have an initial period of babbling; they have specific brain areas for song-learning, just as we have for speech; and they have a sensitive phase in childhood for acquiring song, just as humans have for acquiring language.
The predisposition to develop bipolar disorder is partly genetically inherited.
This is a rare recessive gene disorder that is characterized by shorter height and a predisposition to develop cancer.
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CEO of Professional Science Editing for Scientists @ prosciediting.com