Sentence examples for predisposition of developing from inspiring English sources

Thus, patients who already are at increased risk (due to a genetic predisposition) of developing immune-mediated demyelination, may be at increased risk of developing neurological diseases after the introduction of anti-TNF.

Although the conduct of rigorous and insightful functional genomic studies can be viewed as important in pursuing leads from any GWAS, such studies may have greater importance in the case of anti-cancer agents because of limitations imposed by a relative paucity of patient cohorts, at least compared to studies examining risk, that is, genetic predisposition, of developing cancer.

The study group was very diverse in terms of age and diabetes duration to assess the effect of genetic predisposition on developing BP disturbances.

These studies could help to define new therapeutic targets, new approaches to treatment, and individual indicators of predisposition to developing the disease that might enable the development of effective preventive strategies.

However, 10 families (42% of the series), having at least two melanoma or two NST probands, are strongly suggestive of an inherited predisposition for developing melanoma and NST.

Mutations in such susceptibility genes result in familial predisposition to developing a characteristic spectrum of diseases (collectively known as Hereditary Cancer Syndromes).

The use of SHR to investigate how a genetic predisposition to developing ADHD-like behaviour alters the consequences of early life stress is therefore relevant and appropriate.

Carriers of the human leukocyte antigen (HLA) HLA-B*1502 HLA-B*1502and HLA*3101 andeles, especially of Asian ancestry, demonstrate a predisposition to developing tHLA*1511rse realleles

Patients with Li-Fraumeni syndrome, which results from loss of TP53, have a strong predisposition to developing osteosarcoma [ 16].

The second explanation is that a genetic predisposition increases the probability of developing mood and anxiety disorders.

Hence, DM can accelerate onset and increase severity of disease in individuals with a predisposition to developing tau pathology.