We therefore integrated the nucleosome-DNA interaction model in our analysis, which is based on the principle that certain DNA sequences show a greater predisposition to wrap around the histone octamer and form nucleosomes [ 44].
"There's a predisposition about politicians dancing around the truth," Mr. Benjamin said.
Studies before that have to focus on either the impact on very early breast cancer, which is rare and may be different (e.g. due to genetic predisposition) from breast cancer emerging around menopause, or focus on women whose OC-use patterns are very different from those of other women.
We discuss these perspectives around three topics: smallholders' predisposition to adopt silvopastoral practices, their views about needing external payments to sustain their livelihood and the diffusion of innovative sustainable practices.
You may have a genetic predisposition to a certain layout of weight around your face.
The observed elevation of TIMP-1 in plasma might reflect local pathological processes in or around the rotator cuff, or a genetic predisposition in these patients.
Interestingly, a dysregulated adipose tissue with inappropriate hypertrophy of the abdominal adipose cells was seen around four-times more commonly in individuals with a genetic predisposition for Type 2 diabetes [10], [11].
The gene implicated in predisposition to CD (HLA DQ2 and DQ8) has a worldwide prevalence of around 1%.
In conclusion, the greater density of CD34+ and CD141+ vessels around DCIS associated with invasive carcinoma could reflect a greater predisposition to invade but a direct effect of co-existent invasive carcinoma cannot entirely be ruled out in the present study.
The possibility of an ethnic or genetic predisposition to develop diabetes in this population is supported by epidemiological evidence from around the world [ 22] and India itself where there are over 33 million people diagnosed with diabetes [ 23].
This study design can not exclude the involvement of a rare allele in predisposition to breast or ovarian cancer; for example, CHEK2*1100delC, has a frequency of around 1% and was recently shown to confer a two-fold increased risk of breast cancer [ 34].
