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The interdomain disulfide bond at the C-terminal of the constant region, which plays an important role in Fab stabilization, is predisposed to provide lower production yield than scFvs [ 41].
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In responding to the letter, a spokesman for Mr. Gargano said that if any of the program's $481 million remained after the last grants were awarded to businesses that had applied by the Dec. 31 deadline, "we are predisposed to providing additional assistance to those businesses that were most severely impacted by the events of Sept. 11".
We identified several previously unreported CNV loci that predisposed to or provided protection from OA. Identification of the associated variants at these genomic loci and their potential functional consequences will lead to better understanding of the pathogenesis of OA.
Such chaperones reduce conformational heterogeneity, mask counterproductive surfaces while extending surfaces predisposed to forming crystal contacts, and provide phasing information.
"The President has lit a fire to personalize media, self-selecting 'trusted' news sources that provide only information we're predisposed to accept as factual while disparaging or rejecting everything else," Kessler wrote in an email.
Patients with PHS are predisposed to aspiration or choking, as the bifid epiglottis provides incomplete airway separation during swallowing.
Make sure you understand reimbursement limits, and especially if your pet is a breed genetically predisposed to cancer, consider opting for a plan that provides the most comprehensive coverage available.
In this regard, bulge epithelial stem cells, keratinocytes predisposed to hair follicle fate or keratinocyte precursor cells with plasticity may provide favorable epithelial cell populations.
Genetic biomarkers, such as up-regulation of genes, can provide quantifiable measures of exposure response in those predisposed to disease.
The current study thus provides insights as to why South Asians are predisposed to insulin resistance compared to Caucasians.
These data provide evidence as to why horses with EMS may be predisposed to developing laminitis, potentially as a result of an exaggerated inflammatory response to glycemic and insulinemic responses.
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