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These findings suggest that defined cell types in normal breast tissue may be predisposed to acquiring oncogenic events that result in specific types of cancer.
The risk of infection of heart valves in persons predisposed to acquiring infective endocarditis increases with the following conditions: congenital heart disease, rheumatic fever, major dental treatment, open heart surgery, and genitourinary procedures.
In this analysis, percentage of gastrostomy tubes among home residents served as a proxy for generalized debility within each nursing home, and our findings suggest that more debilitated patients may be more predisposed to acquiring resistant organisms.
Genetics can make a person more predisposed to acquiring an eating disorder.
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Moreover, silencing of NEARS in localized PCa tissue predicts an aggressive clinical course, consistent with the notion that certain PCas may be predisposed to acquire neuroendocrine-like features in a PcG-dependent manner.
Our data suggest a new hypothesis for the origin of ependymoma: that RG in different parts of the CNS are predisposed to acquire distinct genetic abnormalities that transform these cells into CSC of supratentorial, posterior fossa and spinal ependymoma.
Alternatively, considering that the chemical mutagens with which most of these mutant strains were created cause specific nucleobase alterations (e.g., G→A by EMS), certain septin proteins could be predisposed to acquire Ts– mutations if the codons representing critical residues are easily mutated to nonconservative amino acid substitutions (e.g., GGA→AGA and Gly→Arg).
She was predisposed to win.
More likely, the combination of confusion and poor hygiene and ambulatory state in the patient may have predisposed her to acquiring B. procyonis roundworms through ingestion of contaminated soil.
Here, we show that IPF fibroblasts are predisposed to CS and acquire some CS-like features far before reaching cell growth-arrest.
Possible ways of accumulation of mutation in the three steps of the central dogma (DNA-mRNA-Protein) have been studied to trace the mutational effects predisposed to disease consequence and acquiring higher selection pressure.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com