Sentence examples for predictor of efficacy from inspiring English sources

The first category includes antibiotics, such as aminoglycosides, where the best predictor of efficacy is the ratio of peak drug concentration (Cmax) to minimum inhibitory concentration (MIC; Cmax/MIC) [10, 11].

Some antibiotics, such as fluoroquinolones and glycopeptides, are more complex and exhibit both a concentration and time-dependent kill characteristics where the best predictor of efficacy is the ratio of area under the concentration time curve during a 24-hour period (AUC0-24) to MIC (AUC0-24/MIC).

Rather, the level of MIV-150 associated with the cervical tissues appears to be a better predictor of efficacy.

Moreover, the rate of virologic response six months after treatment initiation, a well known predictor of efficacy and adherence [9], [30], [31], was independently associated with interruption in care or death.

Thus, while monitoring the phosphorylation of one or two SRC targets may not predict response to a clinical SRC inhibitor like dasatinib, phosphorylation of a collection of proteins may be a more useful predictor of efficacy.

Intragastric pH >4 HTR is a widely accepted predictor of efficacy of treatments for GERD.

The results of the study will provide information about a) whether CBT adds benefit over and above TAU for ADHD and, b) if CBT is found to be efficacious, potential mechanisms of change and predictors of efficacy.

Here, we argue for routine, early and cumulative screening for genetic predictors of efficacy, as an integrated component of clinical trial analysis.

Less than 20% of drugs are estimated to have common genetic predictors of efficacy that are large enough to inform clinical decision making.

Our approach is broadly applicable to study human immunity and can help to identify predictors of efficacy as well as mechanisms controlling immunity to vaccination.

Moreover, the inclusion of biomarkers as predictors of efficacy is a key step towards a more general mechanism-based strategy.