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Measurement of anti-GAD antibodies has been proposed as a better predictor for the future development of type 1 diabetes in people at high risk [ 50].
Using a similar approach, Warram et al. (4) also demonstrated that insulin resistance was a strong predictor for the future diabetes.
Therefore, we wondered if certain features of the fitness landscape of the early ancestors could be a predictor for the future success of lineages.
The time it takes for plasma glucose concentration to return to or below the FPG concentration during the OGTT also is an important predictor for the future development of type 2 diabetes.
The incremental area under the glucose curve during the OGTT (ΔG0 120) was a strong predictor for the future risk of type 2 diabetes and had an aROC curve (0.770) comparable with that for the 1-h plasma glucose concentration (0.795).
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Birth weight and child growth are important predictors for the future health of a person and for the public health of a population.
Surrogate measures of β-cell function obtained from plasma glucose and insulin concentrations during the OGTT correlate well with β-cell function measured with the gold standard hyperglycemic clamp method and have been shown to be good predictors for the future risk of type 2 diabetes (29, 30).
Of additional significance, NDS has been documented as a reliable strong predictor of the future risk for foot ulceration (1, 15).
This paper has adopted a relatively simple predictor for estimating the future location of a vehicle.
As discussed earlier, models that include a measure of β-cell function would be expected to have a better predictor value for the future risk of type 2 diabetes.
Indeed, questions on subjective cognitive impairments [ 34] and depression [ 35] are good predictors of the future development of, for example, MCI and dementia [ 36].
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