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The resulting candidate survival probe sets were subjected to a supervised analysis [16], which comprises computation of principal components with candidate probe sets, Cox proportional hazards regression analysis using the resulting principal components, and finally prognostic predictor calculation by fitting the predictive prognosis model derived from the Cox regression.
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The best linear unbiased predictor (BLUP) calculation was implemented using a PROC MIXED model, with genotype, location, genotype by location, and replications as random effects [ 47].
For vehicles in fixed-route service, measurements gained during vehicle operation can be used for the design of a predictor for the online calculation of the expected speed profile which is directly related to the load power profile.
Bayes linear discrimination provides much more ductile models because their tuning to new data sets is a rapid and objective procedure that only requires calculation of predictor variable means in the two risk classes and pooled variances and covariances in the whole training set.
Predicted risks from the random intercept model were calculated using only the fixed predictor effects (the marginal risk calculation), or both fixed predictor effects and random cluster effects (the conditional risk calculation).
Thermodynamic related features are considered by all four online predictors but with different calculation methods.
This calculation of predictors indicated that a minimum sample size of 60 participants was necessary.
It is also relevant that our study concerned subjects with two BCs and does not allow calculation of predictors of the occurrence of a second cancer event nor rates of IBR and CBC.
The differences in predicted and observed incidences within some anesthesiologists were slightly smaller for the standard model compared to the marginal risk calculation, because predictors included in the marginal risk calculation did not contain information of the anesthesiologist specific intercept as these predictors were adjusted for the random anesthesiologist effects.
However, their uptake is often limited because they are cumbersome to use, requiring information on many predictors, or complicated calculations.
The linear predictor used for doing this calculation was taken from model 9, which is given in Equation (10).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com