Logistic regression modellings for ACR categories including all potential predictors available in this study were applied.
The predictors available in the data-set included all those categorized as strong or mixed, all but one categorized as moderate, and most of those categorized as weak in Table 1.
As mentioned previously, there is no specific MAP predictor available yet, and researchers in the field usually rely on classic homology searching tools like BLAST and PSI-BLAST (37) to predict MAPs.
As a first step to develop empirical seismic loss models from the predictor variables available in the study database, the regression model forms proposed by Cha (1998) for GDP and seismic intensities, Heatwole and Rose (2013) for magnitude, population, and GDP, and Samardjieva and Badal (2002) for population and magnitude are adopted in this study.
MELD score, gender, use of antibiotics other than rifaximin, reason for admission and hepatitis C are predictors readily available in clinic that can help identify patients at risk for longer length of stay.
We considered predictors available at hospital admission in multivariable logistic regression models to predict poor outcome (modified Rankin Scale [mRS] score 4-5 or death) at 1 month.
Furthermore, perioperative factors such as acute changes in physiology are not reflected in model predictors available at the time of admission.
When a predictor was not available in PreVILIG, we sought to replace the variable with a proxy variable.
After external validation we will assess whether the predictive performance of the PIAMA model remains stable or improves by deleting or adding predictors that are available in the validation data.
Finally, although this study included a large number of predictors, there may have been some important predictors that were not available in the study dataset.
