Sentence examples for predictive of the efficacy of from inspiring English sources
Conclusions: GRT is predictive of the efficacy of a therapeutic regimen, in particular regarding evolution of further resistance mutations.
In summary, we propose that Chk1 could be a biomarker predictive of the efficacy of chemotherapy across different types of tumors with aneuploidy.
Identifying factors predictive of the efficacy of IFX in patients with refractory UC is clinically important.
In contrast, whether BRAF and PIK3CA mutations are predictive of the efficacy of anti-EGFR therapy remains controversial [ 19- 22].
c-KIT is one of the primary targets of imatinib, and mutations in KIT are predictive of the efficacy of the drug in gastrointestinal stromal tumors (GIST) [ 43].
Clinically, tests which are prognostic, but not specifically predictive of the efficacy of cytotoxic therapy, are commonly used to make decisions about such therapy.
Not only serum markers but also hemostatic parameters have been examined as predictive factors of the efficacy of chemotherapy and prognosis.
On the other hand, although recent research has revealed a number of valuable predictive biomarkers of the efficacy of epidermal growth factor inhibitors, no such progress has been made with regard to the treatment with Bev [ 3].
One of the main results is the identification of the NK cells as an interesting predictive factor of the efficacy of belimumab, suggesting that two types of disease can be hypothesised in patients with pSS, the first one being NK cell– and type II IFN driven and not responsive to B-cell targeted therapy and the other B-cell targetedll–driven and more responsive therapymumandtherapy.
Besides the identification of predictive biomarkers, the efficacy of alternative methods to target the IGF pathway should be explored, such as tyrosine kinase inhibitors that target both the IGF-1R and the insulin receptor, given its crossreactivity.
We employ a Bayesian approach involving importance sampling of the posterior predictive distribution to predict the efficacy of a new measurement at reducing the uncertainty of a selected prediction.
