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The third positions of preferred codons in two codon usage groups also paired significantly more often in stems than in loops of mRNA secondary structure predictions, which suggested that codon bias might also affect mRNA stability.

In our analyses using the fixed consensus as a query produced massive under-predictions, or, alternatively, massive over-predictions, which suggests that querying without taking into account the alignment of 5'-leader regions is obviously misleading.

The curves for all Fot families are above the "pure birth" prediction, which suggests that the past rate of duplication per copy was higher than the current one.

These structural features were all chosen in our prediction, which suggests that residues surrounded by others and sheltered from solvents are more likely to be hot spots [ 17].

Our results showed that the ensemble learners among well-tuned TAGGING-assisted QTL models and GBLUP models that come from the same genotypic information improved prediction, which suggests their useful complementation in prediction of complex traits.

For females, LASSO selected the null model as its best prediction model, which suggests that none of the genes were informative in predicting IgE level.

Third, we show that sequence similarity is an important prediction performance determinant, which suggests that experimentally collecting additional quantitative interaction data for underrepresented PDZ domain subfamilies will improve prediction.

The results indicate that the gg2v4 predictions from the updated v4 assembly are typically the same as the predictions on the shorter genome contigs of v3, which suggests that the predictions are not overly sensitive to the length of the contigs used as input.

Our data support a prediction of the developmental hypothesis, which suggests that altricial nestlings gradually increase their glucocorticoid stress response during the nestling stage until exhibiting an adult like profile [48].

More than two thirds of all comparisons show zero prediction of other species distributions, which suggests that most Cyclamen are climatically isolated.

We also find that, the (R2 - R4) logrank statistics can be larger than those of (R1), which suggests that prediction performance can be improved by incorporating higher-order representative features.

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