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The rank sum consensus prediction is robust to the inclusion of random prediction lists (the worst-performing teams predictions were equivalent to random).
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On this site, a preliminary prediction of the reaction classes which, together with a combination of reacting class predictions, is equivalent to the prediction of the metabolite structures (because for each of the considered reactions, it is known which structural fragment is added to or removed from the reacting atom) is performed.
Our permissive calculations of true and false predictions are equivalent to the scoring scheme used previously to evaluate overall SCL prediction [ 2].
So, not submitting a prediction is equivalent to submitting a 'random' prediction in our assessment.
Our prediction is equivalent to considering the bacterial cellular behaviour to be related with biological robustness, as supposing that the bacteria is not seeking for its optimality when undergoing stress response, but seeking for sub-optimality.
Overall, a handful of best-performer teams were identified, while a majority of teams made predictions that were equivalent to random.
The vast majority of the teams' predictions were statistically equivalent to random guesses.
To quote Prill et al. [ 7], 'The vast majority of the teams' predictions were statistically equivalent to random guesses'.
Interestingly, one of the main conclusions of the DREAM3 event was that the vast majority of the teams' predictions were statistically equivalent to random guesses.
While the fit of the clearance and nonclearance versions of the model to past data were equivalent, their predictions of future mortality were different.
Predictions based on profiles of the other mutants tested were equivalent, or worse than the wild-type prediction.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com