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Based on these predictions, we hypothesized that allowing aflibercept to bind to NRP‐bound VEGF would lead to reduced concentrations of bound aflibercept in the plasma, influencing the fit to the clinical measurements.
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However, since model performance measures are defined as functions of the observed outcomes and predictions, we hypothesize that such measures may be optimistic when the predictions are constructed from a set of imputed covariates partly derived from the observed outcomes.
Based on the computational prediction, we hypothesized that dMyc's transcript is a target of miR-308 and that miR-308 is part of the negative feedback regulation of dMyc.
In our second prediction we hypothesized that the training of crossmodal associations between formerly unrelated sounds and images might also induce effects of congruency, that is, activation differences in 2 possible directions: AV-ART-CON > INCON or AV-ART-INCON > CON.
Based on previous studies and computational miRNA target site prediction algorithms, we hypothesized that miR-26a and miR-30c may co-target CTGF.
Using a biological information database and phosphorylation prediction software, we hypothesized that PLK2 phosphorylates TAp73 and inhibits TAp73 function in osteosarcomas.
Both peptide library screening and evolutionary conservation proved to be useful in prediction motifs, we hypothesized that combining chemical enrichment scoring matrixes derived from peptide libraries and conservation analysis would discriminate between classes of proteins that have functional SLiMs and those that do not.
Motivated by our predictions of stress fiber relaxation, we hypothesized that a step increase in equibiaxial stretch would cause a transient increase in MAPK phosphorylation levels.
Each hospital has its own structure and processes, and while patient factors certainly impact the risk of readmission, we hypothesized that predictions models and interventions may be challenging to apply broadly because of the heterogeneity of hospitals.
Objectives: We hypothesized that prediction of OD for determining the optimal tracheal tube size in pediatric patients based on age in months is better than Cole's formula.
Due to the noted lack of homology we hypothesized that prediction of the proper start sites would have been problematic and many signal peptide sites may have been missed.
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