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This year, we have expanded the scope of predictions to include almost all of the award shows.
The honey bee official gene set is biased towards conserved genes, as conservation was a factor in determining which gene predictions to include [ 28].
We now include a new sequence conservation measure, expand our predictions to include 59 new TFs, introduce a web-server, and implement an improved ranking method to reveal the biological features contributing to regulation.
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This review also extends spectrum occupancy prediction to include cooperative prediction.
In CASP8, 57 targets (∼45%) were designated for 'Human/Server' prediction, allowing predictors to include human expert analysis.
The remaining predictions appear to include the true predictions.
The predicted protein of ENSTGUG00000000100 lacks a start codon, but the prediction can be extended based upon an NSCAN prediction (chr28.016.a) to include a putative methionine.
In our study, we further extended the prediction models to include all 11 influenza proteins for the prediction of host tropism.
Two truncated recombinant CCHFV NP antigens were prepared based on results of prediction studies to include epitopic regions and exclude hydrophobic regions that could influence protein expression and solubility.
We also filtered target prediction sets to include only miRanda target loci supported by CLIP-seq data (see Section 2), similar to the miRFunction approach (Li et al., 2014).
Based on our observations regarding the topology of the co-conservation network described above, we hypothesized that extending the function prediction strategy to include the majority function assignment of a cluster, rather than just the neighbors of a protein, would improve prediction.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com