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To assess the accuracy of predicted structure disrupting mutations, we compared our predictions to experimental data obtained on the purine riboswitch using 2D SHAPE (Selective 2'-hydroxyl acylation analyzed by primer extension) [ 52].
Although the extrapolation of the predictions to experimental data is non-trivial, several of the predicted associations could be confirmed on basis of data obtained in L. plantarum and related species (see Results).
While computational methods have advanced significantly, relatively few studies have directly compared model predictions to experimental data.
We first show the efficiency of such a representation by comparing numerical predictions to experimental results.
By detailed comparisons of model predictions to experimental data the performance of the new model is demonstrated.
The two parameters can be determined by comparing numerical predictions to experimental observations of a fracture test.
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In a first step, parameters lumping distance and material constants were estimated by matching a theoretical prediction to experimental data.
This study is aimed at modeling axial-radial reactors and validating the model by comparing its prediction to experimental data.
This, however, is only possible by comparing the IA-prediction to experimental data for the product for each considered endpoint.
Thus, from in silico prediction to experimental validation, Adler and colleagues demonstrate a methodology of integrative genomic analysis that can facilitate the discovery of complex transcriptional mechanisms regulating gene expression signatures.
Part of this is due to the increased complexity of correlated electronic systems that increases the difficulty for theoretical predictions to guide experimental work," he says.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com