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For more information on our current assembly of chicken mucins genes, including a comparison to the ENSEMBL predictions, the reader is referred to our mucin web site [ 27].
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For more details on conformal prediction, the reader is referred to a recent monograph [28].
For a more in-depth explanation of the implementation of conformal prediction, we refer the reader to a recent study by Norinder et al. [26].
Although these results concerning potency agree well with the prediction, we should caution the reader that the experiments are based on our Ca2+ concentration assay and thus do not preclude other possibilities such as destabilization of native states or inhibition of the transition from inactive to active in other ways.
In the following we carefully expose our predictions and leave it to the reader to critically reappraise or re-interpret them, in the light of our results.
These lexical constructs provide interesting clues about predicted events and help the reader to better understand the nature of the predictions made by the SVM classifier.
It is really nice suggestions to explain more on the BBH-LS algorithm, and that will help to increase the reader confidence of our prediction approaches.
Similarly "conventional" is also no "conventional" method but use the two terms "intraspecies homology-based prediction" as well as "interspecies homology-based prediction" instead of "stringent" or, previously "accurate" to not mislead the reader Authors' response: As we discussed in the previous reply, intraspecies/interspecies homology-based prediction are also very confusing to the readers.
We went into some detail about this in the "tool" manuscript in PeerJ, but also here explicitly caution the reader about the value of category 3 predictions.
Sections 1.5, 1.6, and 1.7 give the reader a number of practical algorithms for filtering, smoothing, and prediction.
It is unsurprising that such dramatic predictions of the effects of the epidemic on the structure of the population would strike the reader.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com