Third, while aggregating a bunch of polls for each election reduces the variance, it does not eliminate the bias, so these overconfident predictions pose a problem for aggregate forecasts as well.
Effects of nongenetic inheritance on offspring fitness may translate into long-term consequences for population persistence and adaptation (Vandegehuchte and Janssen 2011), but long-term predictions pose a challenge.
Modelling artificial neural networks for accurate time series prediction poses multiple challenges, in particular specifying the network architecture in accordance with the underlying structure of the time series.
This prediction poses a problem for astrophysicists: If the early generation of stars was ridding galaxies of cool gas, galaxies would soon die, unable to create any new stars and evolve any further.
Despite the amount of effort software engineers have been putting into developing fault prediction models, software fault prediction still poses great challenges.
The average RMSD of the predicted pose to the experiment was 2.0 Å (diverse set), 1.8 Å (phenol-derived predictions), and 1.2 Å (catechol-derived predictions).
My last predictions piece posed the question: will 2013 be a breakthrough year?
A large model uncertainty leads to a large variation in the model prediction, which poses a significant challenge in a geotechnical design.
In the light of the new experiments, however, success of the energy-minimization prediction method poses a new question.
However, a substantial source of error may lie in the high false positive rate of computational miRNA target prediction, which poses a challenge for understanding the impact of miRNAs on gene expression regulation (Alexiou et al. 2009).
However, due to natures of intermittent and difficult prediction, REGs pose new challenges to the reliability of distribution networks.
