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The majority of conserved motifs in both proteins are largely associated with predictions of order (B1, B3, B4, E1, E4 and E5).
The predictor of an α-helix forming Molecular Recognition Feature (α-MoRF) is based on observations that predictions of order in otherwise highly disordered proteins corresponds to protein regions that mediate interaction with other proteins or DNA.
For 10 of these partners, the interactions are mediated by regions experimentally characterized as intrinsically disordered, where PONDR VL-XT detects the majority of these binding regions as short predictions of order within a longer prediction of disorder.
The interactions with 10 of these partners are mediated by region experimentally characterized as IDRs. Figure 3 shows that PONDR® VLXT is able to detect the majority of these binding regions as short predictions of order within a longer prediction of disorder.
It uses a stacked architecture, where PONDR® VLXT is used to identify short predictions of order within long predictions of disorder and then a second level predictor determines whether the order prediction is likely to be a binding site based on attributes of both the predicted ordered region and the predicted surrounding disordered region.
The predictor utilizes a stacked architecture, where PONDR® VLXT is used to identify short predictions of order within long predictions of disorder and then a second level predictor determines whether the order prediction is likely to be a binding site based on attributes of both the predicted ordered region and the predicted surrounding disordered region.
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In addition, this can be useful (from a practical point of view) for the possible modelling of such complexes (their prediction, prediction of order of processes, modelling cis-regulatory modules, etc).
This interaction is shown in Figure 10, where the aIF2γ binding region corresponds to a local prediction of order in the N-terminus of aIF2β.
Nonetheless, it doesn't seem unreasonable to assume that continuous metrics will improve on prediction of ordered categorical metrics in their system.
Classic enhancements in computer architectures are pipelining, instruction and data caching, dynamic branch prediction, out-of-order execution, speculative execution, and fine-grained chip multithreading.
CORRECTION: A May 7th Talk of the Town story on Mel Kiper, Jr., as a predictor of first-round N.F.L. draft picks stated that he got twenty-two per cent right this year; that number applies to his predictions of draft order, while his predictions of who would be picked in the first round came in at eighty-one per cent.
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predictions of doom
predictions of failure
predictions of course
predictions of progress
predictions of chaos
predictions of defeat
predictions of recession
predictions of future
predictions of Experiment
predictions of stardom
predictions of demise
predictions of mass
predictions of catastrophe
predictions of delay
predictions of simulation
predictions of model
models of order
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