Sentence examples for predictions of mutant from inspiring English sources

Predictions of mutant strain behavior in the past have been based on steady state theories such as flux balance analysis (FBA), minimization of metabolic adjustment (MOMA), and regulatory on/off minimization (ROOM).

Specifically, the two goals of expanding the reconstruction of metabolic networks and improving model predictions of mutant viability may be contradictory in some situations.

Analysis of the initial positive, or viable, predictions of mutant phenotypes of SpoMBEL1693 resulted in 65.4% of the positive predictions matching the observed in vivo phenotypes (296 false positives and 560 true positives).

The model allows for predictions of mutants and pharmacological effects because it includes the ethylene receptor.

The method implemented in ANGDelMut has been previously tried and tested, and in addition, the functional loss predictions of mutants have been correlated with known experimental reports.

In silico mutagenesis, performed by deactivating cis-acting sites, provides prediction of mutant expression profiles and identifies global functional activity of cis-acting sites in the gene expression.

We have carried out presymptomatic prediction of mutant gene carrier status in ten individuals with a family history of retinoblastoma.

Also other authors [ 60] have observed that full MD simulation is not more successful in prediction of mutants than simpler approaches, and that the inclusion of nonlocal flexibility of the to-be mutated protein structure led to a higher number of false positive predictions [ 45].

Predictions on mutant, yeast-toxic strains of HET-s suggest similar alternate folds.

Given the absence of high resolution crystal structures of kinase cancer mutants and nature of large conformational changes caused by activating mutations, we focused on understanding local functional effects of cancer mutations rather than attempting to make computational predictions of the mutant structures.

iMM904 was employed for similar studies in predicting the in silico growth phenotypes and was used as a basis for eukaryotic metabolic model's prediction capability of mutant growth phenotypes [ 18].