Sentence examples for predictions of interactions from inspiring English sources

Identifying coevolving positions in protein sequences has myriad applications, ranging from understanding and predicting the structure of single molecules to generating proteome-wide predictions of interactions.

These classification exercises, however, were based entirely on molecular similarity and included no explicit predictions of interactions of compounds with protein targets.

It is therefore highly desirable to improve or develop means for reasonably approximating predictions of interactions.

Examples will be given for possibilities of mechanism-based predictions of interactions which exceed trivialities of simple increases by enzyme induction of enzymatic rates of a given biotransformation pathway leading to a toxic metabolite.

An additional advantage of incorporating this information about the species tree is that non-standard evolutionary events (such as horizontal gene transfer) can be detected along with the predictions of interactions.

Nevertheless, because we do not use network topology information to make de novo predictions of interactions or functional annotations for specific proteins, we expect this potential deficiency to have a less significant effect on our findings.

The high enrichment of co-localization and co-process is consistent with our prediction of interactions and, validates our predicted interactions using gene ontology, and future experimental validation of the high confidence predictions are likely to yield true positive interactions.

We also bolster the prediction of interactions if they, or the PPI that predict them, have been found by more than one type of experiment with the ExperimentScore.

A main challenge lies with the quantitative prediction of interactions between different entities across different scales.

Thus, P2Y14R homology modeling may allow detailed prediction of interactions to facilitate the design of high affinity, selective agonists as pharmacological tools to study the P2Y14R.

Rosetta is used in the Critical Assessment of Prediction of Interactions (CAPRI) experiment, which evaluates the state of the protein docking field similar to how CASP gauges progress in protein structure prediction.