Sentence examples for predictions of combinations from inspiring English sources
Our primary goal was to 1) approximate the size and general shape of the EGFR tail and four of its docking partners and 2) use this information to arrive at reasonable predictions of combinations that might be accommodated on the EGFR tail simultaneously.
Our results hold the promise that predictions of combination effects could be obtained in the future without conducting mixture experiments but by employing modeling approaches.
In relation to certain sensitive hallmarks of disrupted male sexual differentiation, dose addition and independent action proved to be equally useful tools for the prediction of combination effects of mixed-mode antiandrogens.
Toxicological predictions of such combinations must be based on an understanding of the mechanisms of action and interaction of the components of the mixtures.
Efficacy data identified from in vitro and in vivo experiments would then be used for model refinement so more informed predictions of drug combinations can be made in future studies.
Looking ahead, the statistical methodology developed in this work can be further tested and validated with expanded phase II clinical trial data sets, more specific data sets, and in prospective predictions of new combinations moving into phase II studies.
This is often used to make probabilistic structural fracture predictions for combinations of crack length and applied load.
The resultant model could then be used to give predictions for combinations of agents, activating specific mathematical subsections describing human pharmacology.
A wide range of studies has found that human behavior is close to these predictions of optimal combination.
The overlap is determined by dividing the number of overlapping predictions through the total number of predictions of a combination (expressed as percentage).
Additional file 1: Table S6 shows the results of predictions by combinations of the considered methods using the simple majority voting and union approaches for consensus.
