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These theoretical predictions, in combination with experimental data, could be a great asset for the identification of ligand recognition sites and to the drug discovery process.
In order to define all factors involved in the coordinated PlcR-based virulence response in B. cereus, we have undertaken an extensive study to map the complete PlcR regulon in the ATCC 14579 reference strain, utilizing mutagenesis experiments and in silico predictions in combination with proteomics and transcriptomics analyses.
Thus the expression of PD-1 on T-cells may provide different predictions in combination therapy.
The initial set of open reading frames (ORFs) was manually selected from the predictions in combination with the similarity search results.
EVidenceModeler [ 4] was utilized to combine ab initio gene predictions from Augustus and SNAP, the Ensembl Build 65, and the NCBI ref_Anocar2.0 gene predictions, in combination with UCSC reference protein alignments and A. carolinensis transcriptomic data from the PASA assembles.
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We propose a novel model predictive control scheme using a reduced order model for prediction in combination with an error bounding system.
The new scheme employs linear prediction in combination with median filtering.
The numerical prediction, in combination with the measurements, gives insight to the surface aeration performance of stirred tanks.
In addition, identification and characterization of miRNAs and their target genes were established using bioinformatics prediction in combination with 5′-RACE.
We then performed open reading frame (ORF) prediction in combination with SignalP analysis based on whole transcriptome shotgun sequencing (RNAseq) data.
However, combination of IL28B haplotype 2 carrier status with the HLA-C C2C2 genotype, which has previously been reported to improve prediction in combination with IL28B, provides the highest PPV (80%).
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