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The QL model predictions differ substantially from those of the MM, to the point where it may alter decision making.
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We did not consider these models here since they are not directly comparable; however, from our experience these models can also give predictions that differ substantially from BOADICEA (results not shown).
However, because all the models are developed in kNN QSAR modeling by interpolating activities of the nearest neighbor compounds only in the relevant training sets, a special applicability domain (i.e., similarity threshold) should be introduced to avoid making predictions for compounds that differ substantially from the training set molecules.
Beta regression fits the typical distribution of HRQL data better than linear mixed models, however, if focus is on estimating group mean scores rather than making individual predictions, the two methods might not differ substantially.
IPred distinguishes between combinations of prokaryotic predictions and eukaryotic predictions since the structure of gene loci can differ substantially depending on the organism type.
The measured transition frequencies differ substantially from simple theoretical predictions.
Their predictions of how elementary particles should behave often differ substantially.
He thinks they will differ substantially.
But they differ substantially, one from another.
The treatment methods differ substantially between Member States.
But my view appears to differ substantially from Cameron".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com