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These predictions are mainly based on an extrapolation of wind tunnel measurements done on simple structures which are the base of the present design codes.
Current ab initio predictions are mainly focused on small proteins.
The W-FAM-results are not affected by the effective population size since each full-sib family is treated separately, and the genomic predictions are mainly tracing parents' chromosome segments rather than population-wide linkage disequilibrium.
They generally work well when applied to clonal data [ 10, 12] which led to the conclusion that "false" predictions are mainly attributed to the lack of detection of minor populations of CXCR-using variants.
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The congruency (P-value = 1.8 × 10−34) between the two predictions was mainly driven by the large number of SNPs predicted to be benign by PolyPhen and tolerant by SIFT.
Techniques for traffic noise prediction are mainly based on regression analysis, which generally is not good enough to describe the trends of noise.
Genetic prediction is mainly applied in the context of genetic counseling by predicting the risk of genetic disorders with known mono- or oligogenetic modes of inheritance and a certain history of cases in a known family structure, but accurate predictions of genetic predispositions to human diseases should also be useful for preventive and personalized medicine (de los C ampos et al. 2010).
Drug-induced cholestasis (DIC) is poorly understood and its preclinical prediction is mainly limited to assessing the compound's potential to inhibit the bile salt export pump (BSEP).
However, since earlier fracture prediction was mainly carried out through layer curvature or two-dimensional (2D) models, which cannot meet the demands for the tight-oil study and exploration, it is necessary to build three-dimensional (3D) mechanical models in order to achieve the accuracy needed for further research on the unconventional petroleum.
This is generally not due to the prediction of the SPs, instead, the low quality for prediction is mainly based on the not conserved and poorly characterized transit peptide-like sequences.
Especially when dealing with the Grand Challenges, Futures Studies need to attend to the distinctive role of challenging predictions that are mainly based on extrapolated past events by emphasizing on creativity to present true alternatives [9].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com